Senior Associate Scientist/Scientist, Assay Development

Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts.  Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health.

Senior Associate Scientist/Scientist, Assay Development:

We are seeking a highly motivated and experienced Senior Associate Scientist/Scientist to join our custom Assay Development team, who has hands-on experience developing and validating custom ultrasensitive immunoassays for clients.

The ideal candidate will support the full lifecycle of assay development, from initial concept and research to validation and assay transfer. This individual will play a pivotal role in advancing Spear Bio’s new range of custom ultrasensitive immunoassays and assay biomarker programs.

This role is based onsite in our lab in Woburn, MA 5 days/week.

Responsibilities:

• Design, develop, and optimize ultrasensitive blood-based immunoassays to support Spear Bio’s product pipeline.

• Execute immunoassay workflows with a focus on high-throughput and semi-automated platforms.

• Perform comprehensive troubleshooting to resolve technical challenges and improve assay performance.

• Optimize methods for processing different types of clinical samples for assay development.

• Serve as a technical lead for custom assay development projects and interface directly with customers.

Requirements:

• MS or PhD in Biology, Biochemistry, Biomedical Engineering or a related discipline plus minimum of 3 years of academic lab immunoassay development experience; or 1+ year of industry immunoassay development experience.

• Direct experience running immunoassays is required for consideration.

• Hands-on experience utilizing ultrasensitive platforms like Simoa, MSD, Lumipulse, and/or homebrew platforms for novel immunoassay development

• Previous experience with customer assay development is strongly preferred

• Strong experience troubleshooting complex, ultrasensitive immunoassays

• Strong proficiency in molecular biology lab techniques

General Qualifications:

· Self-motivated, with ability to perform complex tasks in an effective manner

· Ability to follow instructions, learn, and grow in a mentorship setting

· Excellent organizational and documentation skills

· Desire to learn about and implement new technologies

We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company.

Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability.

Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.